Methotrexate-Induced Pancytopenia and Mucositis Caused by Medication Error
نویسندگان
چکیده
منابع مشابه
Methotrexate Induced Pancytopenia
The well-reported methotrexate (MTX) toxicities are based on the duration and cumulative dosing of drug. The typical toxicities can be predicted by the timing of drug administration, where mucositis occurs as an earlier effect, while myelosuppression and the sequelae of pancytopenia occur later after MTX administration. Despite these well-known toxicities, low dose MTX therapy can become proble...
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Corresponding author: Edward Chia-Cheng Lai PhD School of Pharmacy Institute of Clinical Pharmacy and Pharmaceutical Sciences College of Medicine National Cheng Kung University No. 1, University Road Tainan 701, Taiwan Phone: +886-6-2353535 E-mail: tb8991010@mail. ncku.edu.tw 1 Department of Pharmacy, Chang Gung Memorial Hospital, Keelung, Taiwan 2 School of Pharmacy, Institute of Clinical Phar...
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Intestinal mucositis is one of the major problems in the patients receiving cancer treatment. Nimesulide is a drug with antioxidant, antiinflammatory and antiulcer features. We aimed to investigate the effect of nimesulide on the small intestine mucositis induced by methotrexate (MTX) in rats. Experimental animals were divided into the control group, MTX group (MTXG) and nimesulide+MTX administ...
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ژورنال
عنوان ژورنال: Ghana Medical Journal
سال: 2020
ISSN: 0016-9560
DOI: 10.4314/gmj.v54i1.9